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DEFINITION: BASE
The information coding part of DNA, the letters of the genetic code. The
sequence of bases on a stretch of DNA (i.e., the sequence of As, Ts, Gs, and Cs)
determines what the DNA does—if it codes for a protein, turns on a gene, or
whatever. In protein-coding regions, three base pairs code for a single amino
acid. For example, the base pair sequence ATG codes for the amino acid
methionine. In a strand of DNA, bases are paired and are lined up across from
one another: A pairs with T and G pairs with C.
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